RESEARCH PROGRESS OF PHENOTHIAZINE COMPOUNDS OF DIOXOPROMETHAZINE HYDROCHLORIDE

Tingting Zhao, Chuanbo Dai, Yuting Gao

ABSTRACT:With the development of science and technology and the progress of society, people are paying more attention to the environment and energy while paying attention to production and benefits. Phenothiazine compounds are very important heterocyclic compounds. They have been widely used in medicine, electroluminescent materials, solar cells, polymerization inhibitors, antioxidants, antioxidants and other fields in recent years. This article briefly introduces the application and technological progress of phenothiazine compounds. Dioxopromazine hydrochloride is a type of phenothiazine compounds, which have high application and research value in the aspects of relieving cough, relieving asthma, eliminating phlegm ,antihistamine and so on. In this paper, we will summarize the oxidation processes commonly used in the production of dioxaprozin hydrochloride to make it more green and efficient,and provide a reference for the development of dioxopromazine hydrochloride, and look forward to the future production process and research direction.

Keywords:Phenothiazine, Dioxopromethazine hydrochloride, Oxidation reaction, Synthesis.